![]() "They are scared by what they hear from friends and read from Dr. Many men avoid statins because they fear possible side effects, says Dr. (You assess your estimated 10-year risk at: /ascvd.)Įven people with a lower LDL cholesterol level - for example, 100 mg/dL - should consider taking a statin if they have other risk factors, such as diabetes, a family history of heart disease before age 55, smoking, or high blood pressure. Statins also can benefit otherwise healthy people with elevated LDL cholesterol levels of 160 milligrams per deciliter (mg/dL) or higher, and those with a 10-year risk of cardiovascular disease at 7.5% or higher. Who needs statins? Anyone who has coronary artery disease or other arterial disease caused by plaque buildup should be on a statin, even if the person has a normal cholesterol profile. Also, statins help prevent plaques from breaking open and releasing chemicals that stimulate blood clot formation, which is the cause of most heart attacks. Statins have anti-inflammatory properties, and inflammation is a known contributor to plaque buildup. High LDL levels can create plaque buildup in the arteries, which can block blood flow, and raise your risk of a heart attack or stroke.īut the benefits of statins go beyond just lowering LDL cholesterol. Statins work to lower the production of low-density lipoproteins (LDL), or "bad" cholesterol, by blocking an enzyme in the liver that helps make cholesterol. "Yet, men who can benefit from statin therapy sometimes avoid it because they misunderstand how the drug works, including the nature and frequency of side effects, as well as the larger role statin therapy can take in managing their longer-term health." The role of statins Randall Zusman, director of the Division of Hypertension at the Harvard-affiliated Massachusetts General Hospital Heart Center. "Statins have a role in men's health under the right circumstances," says Dr. Still, many people who could benefit from the drug don't take it. Statins have been doing what they do - lowering cholesterol to help prevent cardiovascular disease - for more than three decades. 16, 2020.Statins can help men lower their risk of heart attack and stroke, yet many resist them. Francisco Lopez-Jimenez (expert opinion).Low density lipoprotein cholesterol lowering with drugs other than statins and PCSK9 inhibitors. Cholesterol medications and lifestyle choices can work together to help reduce your risk of heart attacks and stroke. It's also still important to follow a healthy diet and get enough exercise. Most cholesterol medications lower cholesterol with few side effects, but effectiveness varies from person to person. It appears that the expectation of the side effect makes it more likely to occur. In studies where participants don't know if they're getting a statin or a placebo, muscle pain is a common complaint in both groups. In many people, the muscle pain often associated with statins may not actually be caused by the drug. Prescription versions include Lovaza, Omacor and Vascepaīelching, fishy taste, indigestion may increase risk of bleeding ![]() The statin component decreases LDL and triglycerides the calcium channel blocker lowers blood pressureįacial and neck flushing, dizziness, heart palpitations, muscle soreness and pain, increased blood sugar levels, constipation, nausea, diarrhea, stomach pain, cramps, elevation of liver enzymesĭecrease triglycerides modestly decrease LDL increase HDLįacial and neck flushing, itching, stomach upset, increase in blood sugar Stomach pain, fatigue, gas, constipation, abdominal pain, cramps, muscle soreness, pain and weaknessĬombination calcium channel blocker and statin Muscle spasms and joint pain, including acute goutĬonstipation, bloating, nausea, gas, heartburnĬombination cholesterol absorption inhibitor and statinĭecreases LDL and triglycerides increases HDL ![]() Itching, swelling, pain or bruising at injection site Stomach pain, diarrhea, fatigue, muscle soreness avoid during pregnancy and lactationĭecrease LDL usually reserved for people who have a genetic condition that causes very high LDL levels or people with heart disease who cannot tolerate statins or other cholesterol lowering drugs Muscle pain, increased blood sugar levels, constipation, nausea, diarrhea, stomach pain, cramps, elevation of liver enzymesĭecreases LDL slightly decreases triglycerides slightly increases HDL Drug classĭecrease LDL and triglycerides slightly increase HDL Here's an overview of the pros and cons for common classes of cholesterol medications. Your doctor might suggest a single drug or a combination of cholesterol medications. ![]()
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